Biochemistry and Clinical Biochemistry Department, Faculty of Veterinary Medicine, Benha University

INSTITUTE OF MEDICAL BIOCHEMISTRY FIRST FACULTY OF MEDICINE, CHARLES UNIVERSITY IN PRAGUE Electrophoresis in biochemistry

Biochemistry & Medicine

Biochemistry can be defined as the science of the chemical basis of life (Gk bios “life”). The cell is the structural unit of living systems. Thus, biochemistry can also be described as the science of the chemical constituents of living cells and of the reactions and processes they undergo. By this definition, biochemistry encompasses large areas of cell biology, molecular biology, and molecula...

Department of Biochemistry & Molecular Biology

Alkbh1 is a human homolog of the Escherichia coli AlkB protein that directs DNA repair by removing alkylation damage to DNA bases. While the in vivo role of Alkbh1 is still unknown, the protein was recently shown to possess abasic site lyase activity in vitro and to cleave abasic sites according to a betaelimination mechanism. Surprisingly, Alkbh1 forms a covalent adduct to the 5?-DNA product. ...

Department of Biochemistry & Molecular Biology

Poster Presentations Wednesday, April 11, 2007 1 floor of the Biochemistry Building 3:00 – 5:00 p.m.

Department of Biochemistry & Molecular Biology

Activation-Induced Deaminase (AID) protein functions in class switch recombination and somatic hypermutation in mammalian cells. The AID protein deaminates cytidine sites in single stranded DNA. We designed and constructed an expression plasmid that encodes AID as a recombinant fusion protein. Our construct includes an N-terminal maltose binding protein as a solubility and expression tag follow...